No doubt about it, the nightlife in San Francisco is some of the best in the world. On any given night of any given week you have the opportunity to see the best bands, biggest dj's and hottest rising artists in the world at nightclubs, concert venues or one of the dozens of street fairs and festivals that the city has become famous for. With so much to choose from, how do you make sure you end up at the right party spot and not some cheesy tourist trap? Read "The MetroWize Hip Guide to Partying in San Francisco" that's how.

Ruby Skye
Location: 420 Mason St. (Union Square)
Ruby Skye is hands down the biggest, most decadent club in San Francisco. Don’t let that scare you away though, it knows how to throw a party. Week after week, the biggest DJ talent in the world comes through there. Sasha, Carl Cox, Tiesto… This is where they come. The venue is massive and the sound system is the best in the city.
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The Fillmore
Location: 1805 Geary (Fillmore)
The historic Fillmore Theater has played host to just about every rockstar that ever became a rockstar. From the Grateful Dead to Smashing Pumpkins, playing the Fillmore means you have made it to the big leagues. The tradition continues today with the best up and comers playing nearly every night of the week. If you are a music lover, you owe it to yourself to experience a show here.
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Mezzanine
Location: 444 Jessie St. (SOMA)
One of the best things about Mezzanine is that they don’t cater to any specific crowd. DJ events, live music, gay nights, whatever… They do it all. Whatever the event, it’s always big. The staff can not be beat from cool bouncers to great bartenders, the sound system rocks and they manage to never let it get so packed that it’s uncomfortable.
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Mighty
Location: 119 Utah St. (Potrero)
Tucked away deep in Potrero, Mighty has become known as THE place for breaks and burning man related events. This is another place with killer sound (monster stack speakers actually), friendly staff and a relaxed vibe. It’s a destination spot so come with plans to stick around for the long haul.
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Supper Club
Location: 657 Harrison St. (SOMA)
If there is one thing that the Dutch do well, it’s partying. So when they Dutch company that runs Supper Club opened one up here in San Francisco, we were all chomping at the bit to get a peak at this performance/dance/miami-esque club. While the drinks can be madly expensive, the décor and vibe here make up for it.
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The Independent
Location: 628 Divisadero St.
Despite the parking situation outside and the bathroom situation inside, these guys have a knack for booking good acts, especially in the Jam Band scene. Formerly the Justice League, the basic box venue did a slight remodel a few years back and re-opened to become one of the best mid-sized venues in San Francisco.
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Temple Nightclub
Location: 540 Howard St. (SOMA)
Temple is a relative new comer to the San Francisco nightlife scene and it's definitely worth checking out. As a major venue (one of the largest in the city with 4 different rooms), the headliners are usually national, if not international, acts. Temple is part of a larger project called the Zen Center, which includes restaurants, a spa, yoga shop and sound studios.
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The End Up
Location: 401 6th St. (SOMA)
The End Up is perfectly named, that’s for sure. This is actually where every one who refuses to go home after a night of heavy drinking and partying “ends up”. With a huge outdoor patio, great dance floor and sound system and parties that rock all day and night long, you really can't miss with the End Up.

DNA Lounge
Location: 375 11th St. (SOMA)
DNA Lounge had it’s hey day a few years back but they still bring in killer shows, have one of the best sound systems in the city, super friendly and courteous staff and they have a late night permit so the parties don't have to stop when the booze does. This is a big club with a big club sound system but the vibe usually feels very cozy.
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Temple
Location: 540 Howard St. (SOMA)
Temple nightclub is one of the newest additions to the San Francisco nightlife scene. This 4 room mega club has a capacity of 1000+ and as a major venue, the headliners are usually national acts, if not international. Temple is the first part of Paul Hemming's (the owner) master plan called the Zen Center, which will be a complex complete with spas, restaurants and other establishments.
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